Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00671 |
Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Adipsin,CFD,ADN,Complement |
Rhesus | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Rhesus macaq... | |||
TMPK-00790 |
Complement factor H/CFH Protein, Human, Recombinant (His)
ARMD4,AHUS1,H factor 1,HF1,AMBP1,FH,FHL1,H... |
Human | HEK293 Cells |
Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self)... | |||
TMPK-00755 |
Complement Factor D/CFD Protein, Human, Recombinant (hFc)
C3 convertase activator,DF,AMBP-1,EC 3.4.21,EC 3.4.... |
Human | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Human, Recom... | |||
TMPY-02183 |
Complement Factor D/CFD Protein, Human, Recombinant (His)
PFD,DF,complement factor... |
Human | HEK293 Cells |
Complement Factor D/CFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P00746. |